Awareness of nursing students towards cancer and their comparison with medical students

Background: Cancer is the 2nd leading cause of mortality worldwide. The three leading cancers in India are cervical cancer, breast cancer and upper aerodigestive tract carcinoma. Cervical carcinoma is the 2nd most common cancer in women next to breast carcinoma. This study has been done to assess the knowledge, causation and preventive methods about the common cancers in India amongst Medical and Nursing students in a tertiary care center in rural Kerala. Preventive measures and early diagnosis of cancer can lead to decrease in mortality and morbidity. This can be achieved by creating awareness. A special emphasis has been made regarding cervical cancer and HPV vaccination in this study.Methods: A total of 337 medical and 148 nursing students from 1st year to final year were included in this study and the results were analysed by descriptive statistics.Results: Out of 337 medical and 148 nursing students, there was significant difference in knowledge between pretest/posttest and amongst the medical/nursing students. Medical students were found be more aware about the cancer, their causation and preventive methods as compared to the nursing students. 76.4% of nursing students were aware about the role of HPV (Human Papilloma Virus) in the causation of cervical cancer pretest. 98.6% of nursing students were aware about the role of HPV in causation of cervical cancer posttest following a short lecture. Following a short lecture both medical and nursing students were found to have more awareness.Conclusions: Creating awareness to the medical and nursing students who are intouch with the community and the patients is essential. Targeted health education in very important in creating a great impact about the knowledge of cancer in the community, thereby leading to decrease in mortality and morbidity

The CMBR ISW and HI 21-cm Cross-correlation Angular Power Spectrum

The late-time growth of large scale structures (LSS) is imprinted in the CMBR anisotropy through the Integrated Sachs Wolfe (ISW) effect. This is perceived to be a very important observational probe of dark energy. Future observations of redshifted 21-cm radiation from the cosmological neutral hydrogen (HI) distribution hold the potential of probing the LSS over a large redshift range. We have investigated the possibility of detecting the ISW through cross-correlations between the CMBR anisotropies and redshifted 21-cm observations. Assuming that the HI traces the dark matter, we find that the ISW-HI cross-correlation angular power spectrum at an angular multipole l is proportional to the dark matter power spectrum evaluated at the comoving wave number l/r, where r is the comoving distance to the redshift from which the HI signal originated. The amplitude of the cross-correlation signal depends on parameters related to the HI distribution and the growth of cosmological perturbations. However the cross-correlation is extremely weak as compared to the CMBR anisotropies and the predicted HI signal. As a consequence the cross-correlation signal is smaller than the cosmic variance, and a statistically significant detection is not very likely.Comment: 13 pages, 4 eps figures, submitte

The angular power spectrum measurement of the Galactic synchrotron emission in two fields of the TGSS survey

Characterizing the diffuse Galactic synchrotron emission at arcminute angular scales is needed to reliably remove foregrounds in cosmological 21-cm measurements. The study of this emission is also interesting in its own right. Here, we quantify the fluctuations of the diffuse Galactic synchrotron emission using visibility data for two of the fields observed by the TIFR GMRT Sky Survey. We have used the 2D Tapered Gridded Estimator to estimate the angular power spectrum (Cℓ) from the visibilities. We find that the sky signal, after subtracting the point sources, is likely dominated by the diffuse Galactic synchrotron radiation across the angular multipole range 240 ≤ ℓ ≲ 500. We present a power-law fit, Cℓ=A×(1000l)β⁠, to the measured Cℓ over this ℓ range. We find that (A, β) have values (356 ± 109 mK2, 2.8 ± 0.3) and (54 ± 26 mK2, 2.2 ± 0.4) in the two fields. For the second field, however, there is indication of a significant residual point source contribution and for this field we interpret the measured Cℓ as an upper limit for the diffuse Galactic synchrotron emission. While in both fields the slopes are consistent with earlier measurements, the second field appears to have an amplitude that is considerably smaller compared to similar measurements in other parts of the sky

Involvement of B cells in non-infectious uveitis

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/Non-infectious uveitis—or intraocular inflammatory disease—causes substantial visual morbidity and reduced quality of life amongst affected individuals. To date, research of pathogenic mechanisms has largely been focused on processes involving T lymphocyte and/or myeloid leukocyte populations. Involvement of B lymphocytes has received relatively little attention. In contrast, B-cell pathobiology is a major field within general immunological research, and large clinical trials have showed that treatments targeting B cells are highly effective for multiple systemic inflammatory diseases. B cells, including the terminally differentiated plasma cell that produces antibody, are found in the human eye in different forms of non-infectious uveitis; in some cases, these cells outnumber other leukocyte subsets. Recent case reports and small case series suggest that B-cell blockade may be therapeutic for patients with non-infectious uveitis. As well as secretion of antibody, B cells may promote intraocular inflammation by presentation of antigen to T cells, production of multiple inflammatory cytokines and support of T-cell survival. B cells may also perform various immunomodulatory activities within the eye. This translational review summarizes the evidence for B-cell involvement in non-infectious uveitis, and considers the potential contributions of B cells to the development and control of the disease. Manipulations of B cells and/or their products are promising new approaches to the treatment of non-infectious uveitis

Awareness of medical students towards cancer

Background: Cancer is the second leading cause of mortality worldwide. Amongst the cancers, the three leading cancers in India which causes high mortality and morbidity includes cervical cancer, breast cancer and upper aerodigestive tract carcinoma. High mortality and morbidity due to cancers can be reduced by preventive measures and early diagnosis of cancer, which can be achieved by creating awareness.Methods: A total of 337 medical students from 1st year to 4th year (1st year students-preclinical, 2nd year students-paraclinical and 3rd and 4th year students- clinical students) were included in this study and the results were analysed by descriptive statistics, Pearson’s Chi square test and paired ‘t’ test.Results: Out of 337 students, 120 were males, 204 were females and 13 students have not mentioned their gender. There was significant difference in knowledge of the students between pretest and posttest (following a short lecture) and amongst the preclinical, paraclinical and clinical students. Clinical students were found be more aware about the cancer compared to the preclinical and paraclinical students.Conclusions: Creating awareness to the medical students who are future doctors is the need of the hour. A short talk on cancer awareness can create a great impact on the awareness

HI power spectrum of the spiral galaxy NGC628

We have measured the HI power spectrum of the nearly face-on spiral galaxy NGC628 (M74) using a visibility based estimator. The power spectrum is well fitted by a power law $P(U)=AU^{\alpha}$, with $\alpha =- 1.6\pm0.2$ over the length scale $800 {\rm pc} {\rm to} 8 {\rm kpc}$. The slope is found to be independent of the width of the velocity channel. This value of the slope is a little more than one in excess of what has been seen at considerably smaller length scales in the Milky-Way, Small Magellanic Cloud (LMC), Large Magellanic Cloud (SMC) and the dwarf galaxy DDO210. We interpret this difference as indicating a transition from three dimensional turbulence at small scales to two dimensional turbulence in the plane of the galaxy's disk at length scales larger than galaxy's HI scale height. The slope measured here is similar to that found at large scales in the LMC. Our analysis also places an upper limit to the galaxy's scale height at $800\ {\rm pc}$ .Comment: 4 Pages, 2 Figures, 1 Table. Accepted for Publication in MNRAS LETTER

Inheritance of parthenocarpy in gynoecious cucumber (Cucumis sativus L.) cultivar PPC-2

The gynoecious and parthenocarpic inbred line, Pant Parthenocarpic Cucumber-2 (PPC- 2) was crossed with Indian monoecious and non-parthenocarpic cultivar Pusa Uday to develop F1, F2, B1 and B2 to determine the inheritance of parthenocarpy.The crop was grown under insect proof net house of 40 mesh. The pistillate buds were covered using butter paper bags before anthesis to prevent out-crossing.The observations were recorded separately for the development of early parthenocarpic fruits (i.e.1-7th nodes), late parthenocarpy (8th and above nodes) and non-parthenocarpic fruits. In F1 generation, out of 40 plants screened, 2 plants produced parthenocarpic fruits at lower nodes (1-7th nodes), 37 plants produced parthenocarpic fruits at upper nodes (8th and above), whereas,only 1 plant that did not produced any fruit was considered as non-parthenocarpic. The segregation of F2 population and test crosses for parthenocarpic fruit development suggested that parthenocarpy in gynoecious and parthenocarpic cucumber line PPC-2 is under the control of incomplete dominant gene

HI Fluctuations at Large Redshifts: I--Visibility correlation

We investigate the possibility of probing the large scale structure in the universe at large redshifts by studying fluctuations in the redshifted 1420 MHz emission from the neutral hydrogen (HI) at early epochs. The neutral hydrogen content of the universe is known from absorption studies for z<4.5. The HI distribution is expected to be inhomogeneous in the gravitational instability picture and this inhomogeneity leads to anisotropy in the redshifted HI emission. The best hope of detecting this anisotropy is by using a large low-frequency interferometric instrument like the Giant Meter-Wave Radio Telescope (GMRT). We calculate the visibility correlation function <V_nu(u) V_nu'(u)> at two frequencies nu and nu' of the redshifted HI emission for an interferometric observation. In particular we give numerical results for the two GMRT channels centered around nu =325 and 610 MHz from density inhomogeneity and peculiar velocity of the HI distribution. The visibility correlation is ~10^-9 to 10^-10 Jy^2. We calculate the signal-to-noise for detecting the correlation signal in the presence of system noise and show that the GMRT might detect the signal for integration times ~ 100 hrs. We argue that the measurement of visibility correlation allows optimal use of the uncorrelated nature of the system noise across baselines and frequency channels.Comment: 17 pages, 2 figures, Submitted to JA

Age-related change in flicker thresholds with rod- and cone-enhanced stimuli

Purpose Rod and cone photoreceptor-specific tests can be time-consuming. A new non-invasive test is described. The test is based on the measurement of flicker modulation thresholds with rod- and cone-enhanced visual stimuli, which requires only minimum adaptation time. Here, we investigated how the rod-and cone-mediated flicker thresholds vary with age. Methods Monocular thresholds with rod and cone–enhanced stimuli were measured in 140 healthy adults, (age range: 18–75 years), foveally (0°) and at four parafoveal locations, at an eccentricity of 5° in each of the four quadrants using five, adaptive, interleaved staircases. Temporal frequencies, stimulus sizes, background luminance and spectral composition, were adjusted appropriately to achieve approximately 1 log unit separation in sensitivity between the rod- and cone-enhanced stimuli. Spectrally calibrated, ‘neutral density’ filters were used to enable adequate control of display luminance for rod enhanced stimuli. Results The magnitude of central and parafoveal rod thresholds was significantly higher than the central and parafoveal cone thresholds, respectively (p 45 years (Spearman correlation, ρ = 0.74, p < 0.001) compared to age ≤ 45 years (ρ = 0.41, p < 0.001). Conclusions Thresholds with rod- and cone-enhanced stimuli are largely invariant below 45 years of age and increase rapidly above this age. This age-wise normative database can be used as an effective functional-marker to assess photoreceptor sensitivities in retinal diseases

Business process modelling and visualisation to support e-government decision making: Business/IS alignment

© 2017 Springer-Verlag. The final publication is available at Springer via https://doi.org/10.1007/978-3-319-57487-5_4.Alignment between business and information systems plays a vital role in the formation of dependent relationships between different departments in a government organization and the process of alignment can be improved by developing an information system (IS) according to the stakeholders’ expectations. However, establishing strong alignment in the context of the eGovernment environment can be difficult. It is widely accepted that business processes in the government environment plays a pivotal role in capturing the details of IS requirements. This paper presents a method of business process modelling through UML which can help to visualise and capture the IS requirements for the system development. A series of UML models have been developed and discussed. A case study on patient visits to a healthcare clinic in the context of eGovernment has been used to validate the models